Advantages and Applications of Intelligent Animal Breeding Cage Systems in Laboratory Projects
创建于05.28
In modern laboratory projects, the breeding environment of experimental animals plays a crucial role in the accuracy and reliability of experimental results. With the continuous advancement of technology, intelligent animal breeding cage systems have emerged, bringing revolutionary changes to the breeding of laboratory animals. Guangzhou Cleanroom Construction Co., Ltd., as a professional manufacturer of purification equipment and cleanroom engineering, will introduce in detail the advantages and applications of intelligent animal breeding cage systems in laboratory projects.
I. Introduction to Intelligent Animal Breeding Cage Systems
Intelligent animal breeding cage systems, such as the Individual Ventilated Cage (IVC) system, are highly efficient animal breeding equipment featuring independent supply and exhaust ventilation design. It is mainly composed of an intelligent main unit, sealed cage boxes, and a ventilation cage rack. Its working principle is that air, after being filtered by primary and HEPA high-efficiency filters (with a filtration efficiency of ≥99.997%), supplies clean air independently to each cage box while exhausting waste gas independently, effectively preventing the spread of pathogens between cages.
II. Demonstration of Core Advantages
(I) Eliminating Cross - Infection and Ensuring Experimental Rigor
1. Independent Ventilation Design: Each cage box has an independent supply and exhaust ventilation system, ensuring that the air in each cage box does not cross - contaminate with others. This greatly reduces the risk of pathogen transmission between animals in different cage boxes. For experiments with extremely high requirements for the health status of experimental animals, such as gene - edited mouse experiments and immunodeficient animal experiments, it can effectively ensure that experimental results are not interfered by external pathogens, making experimental data more accurate and reliable.
2. Sealed Protection: The cage boxes adopt silicone gaskets and non - invasive docking structures, providing excellent airtightness. Additionally, the self - closing valve design further reduces the possibility of contamination during daily operations, such as changing bedding and adding food, providing a safe and clean living environment for experimental animals.
(II) Energy Conservation and Cost Reduction
1. Low Requirements for Room Environment: Compared with traditional barrier systems, intelligent animal breeding cage systems have lower dependence on the overall environment of the laboratory room. They do not need to maintain a high - cleanliness environment for the entire room like traditional systems, thus reducing the use of high - energy - consuming air - handling equipment. The operating costs can be reduced by more than 30%, significantly saving the laboratory's operating costs.
2. Reduced Bedding Replacement Frequency: Through the design of low ammonia concentration and humidity inside the cages, the contamination rate of bedding can be effectively slowed down, thereby reducing the frequency of bedding replacement. This not only saves a large amount of bedding procurement costs but also reduces the workload of laboratory personnel for bedding replacement, improving work efficiency.
(III) Double Improvement of Animal Welfare and Research Quality
1. Low Noise and Vibration: The operating noise is ≤55dB (some advanced models are as low as 45dB), far lower than the national standard. The quiet environment can prevent animals from having stress reactions, keeping them in a more natural physiological state. For example, in some behavioral experiments, without noise interference, the behavior of animals can more accurately reflect the real situation, helping to improve the quality of research data.
2. Constant Temperature and Pressure Environment: The system can precisely control the air velocity ≤0.2m/s, maintain stable pressure differences (0 - 20Pa), and keep suitable temperature and humidity inside the cages. A stable and suitable environment is conducive to ensuring the health of animals, keeping their physiological indicators relatively stable, providing a more reliable experimental model for scientific research, and enhancing the accuracy and reproducibility of research results.
3. Intelligent Day - Night Mode: The main unit can automatically switch operating parameters according to the settings to simulate the natural light cycle. This is crucial for regulating the physiological rhythm of animals. For example, in research on the biological clock, a light cycle consistent with natural laws can make the physiological state of animals closer to the actual situation, avoiding deviations in experimental results caused by artificial light interference.
(IV) Intelligent Management and Convenient Operation
1. Touch - Screen Control and Remote Monitoring: The system is equipped with a liquid crystal screen that can display key parameters such as temperature, humidity, and pressure difference in real - time. Researchers can also remotely monitor and manage the system using mobile phones or computers through network connection. Once abnormal parameters occur, the mobile phone SMS alarm function will promptly notify relevant personnel, ensuring that problems can be addressed in a timely manner and maintaining the stability of the experimental animal breeding environment.
2. Flexible Expandability: The cage racks support single - sided and double - sided configurations and can be flexibly adjusted according to the actual space size of the laboratory animal room and breeding scale requirements. Whether it is for the breeding of a small number of animals in a small - scale laboratory or large - scale animal experiments in a large - scale research institution, it is applicable.
(V) Safe, Reliable, and Durable Materials
1. High - Temperature and High - Pressure Resistant Cage Boxes: Cage boxes are usually made of materials such as PPSU and PEI, which can withstand sterilization at 134℃. This kind of material can not only effectively kill various pathogens, ensuring the hygiene and safety of the cage boxes, but also has high transparency, facilitating laboratory personnel to observe the status of animals at any time and promptly detect animal health problems or behavioral changes.
2. 304 Stainless Steel Cage Racks: The cage racks are made of 304 stainless steel, which has excellent corrosion resistance and is easy to clean. Its sturdy and durable characteristics enable a service life of more than 10 years, reducing the frequency of equipment replacement and long - term use costs.
III. Practical Application Cases
Take the drug research and development laboratory of a large pharmaceutical company as an example. After introducing the intelligent animal breeding cage system, during the toxicity test experiments of new drugs, due to the independent ventilation and sealed protection design of the system, cross - infection between different experimental groups of animals was avoided. This ensured that the health status of each experimental animal was only affected by the drug factor, enabling the experimental data to more accurately reflect the toxic reactions of the drugs and providing a reliable basis for drug research and development. At the same time, the advantage of energy conservation and cost reduction also saved a large amount of operating costs for the laboratory. In addition, the intelligent day - night mode and good environmental control kept the experimental animals in the best physiological state, improving the success rate and reproducibility of the experiments.
Another example is a life science research laboratory in a university. When breeding and conducting experiments on gene - edited mice, through the remote monitoring function of the intelligent animal breeding cage system, researchers can understand the breeding environment parameters of the mice at any time even when they are not in the laboratory and adjust the relevant settings in a timely manner. This has greatly improved the convenience of the experiments and management efficiency, ensuring the smooth progress of gene - edited mouse experiments.
IV. Professional Services of Guangzhou Cleanroom Construction Co., Ltd.
Guangzhou Cleanroom Construction Co., Ltd. has rich experience and a professional technical team in the field of intelligent animal breeding cage systems. We can not only provide customers with high - quality intelligent animal breeding cage system products but also offer personalized laboratory engineering solutions according to the specific requirements of different laboratories. These solutions include one - stop services such as cleanroom design and construction, equipment installation and commissioning, and after - sales maintenance. We are committed to creating a safe, efficient, and comfortable breeding environment for experimental animals, facilitating the smooth progress of scientific research work.
Intelligent animal breeding cage systems have many significant advantages in laboratory projects, bringing higher standards and better experiences to the breeding of experimental animals. Guangzhou Cleanroom Construction Co., Ltd. looks forward to working with you to jointly promote the development and progress of laboratory projects and contribute to the cause of scientific research. If you have any requirements or questions regarding intelligent animal breeding cage systems or laboratory projects, please feel free to contact us.
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