Analysis of Xenon Light Pass Box: Principles, Safety and Application Points

Created on 2025.07.03

1. Disinfection Principle of Xenon Light Pass Box

The xenon light pass box sterilizes materials using high-intensity ultraviolet (UV) rays and ozone generated by the xenon lamp:
  • UV light at ~254nm destroys microbial DNA, preventing reproduction.
  • UV light also converts oxygen into ozone, which oxidizes and kills microorganisms.
This combination ensures rapid, efficient sterilization of materials and the pass box interior, maintaining a clean and sterile environment for material transfer.
Industrial cleanroom equipment with digital display.

2. Safety of Xenon Light Transfer Cabinet

Under normal operation and following specifications, the xenon light pass box is safe for humans.
Potential risks if misused:
  • Direct UV exposure: skin burns, erythema, eye pain, decreased vision.
  • High ozone concentration: respiratory irritation, cough, chest discomfort.
Safety measures:
  • Equipped with interlock devices to prevent opening during disinfection.
  • Operators must follow procedures and avoid opening the cabinet during sterilization.

3. Three Basic Principles

  1. One-way transfer principle: Materials should only move one way between clean and non-clean areas to prevent cross-contamination.
  2. Qualified disinfection principle: All materials must meet disinfection standards before transfer.
  3. Standardized operation principle: Operators must follow procedures strictly, including loading, unloading, and starting/stopping disinfection programs.

4. Role and Applications

The xenon light pass box is used for material transfer between clean areas, non-clean areas, or areas of different cleanliness levels, ensuring:
  • Disinfection of transferred materials.
  • Reduction of pollutants entering the clean area.
  • Maintenance of cleanroom standards.
Applications:
  • Pharmaceutical production: Raw materials, packaging materials, ensuring drug quality.
  • Biological laboratories: Samples, petri dishes, preventing external contamination and spread of harmful microorganisms.

5. Can Xenon Light Pass Box Transfer Mice?

No. The pass box is not designed for live animals, especially mice:
  • Size may not fit; forced transfer can damage equipment.
  • Mice carry pollutants and pathogens; disinfection may not fully remove them.
  • Live animal transfer poses biological safety risks and violates clean environment management requirements.

6. Conclusion

The xenon light pass box is an essential auxiliary device in clean environments, ensuring safe, sterile material transfer. By understanding its disinfection principles, following usage guidelines, and operating correctly, laboratories, cleanrooms, and production facilities can maintain high cleanliness standards, protect operators, and improve overall operational efficiency.
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